Alnylam & the Science of RNAi

Explore a library of educational resources about RNA interference (RNAi), the science behind Alnylam's FDA-approved products and clinical pipeline, and find out more about our small interfering RNA (siRNA) delivery platforms.

Ribosome-producing disease-causing protein from mRNA
Ribosome-producing disease-causing protein from mRNA

Click on the links below to learn more about how RNAi can be used to "silence" gene expression and the production of proteins that cause or contribute to disease.

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Summary of RNA Interference

An overview of RNAi discovery, how RNAi works, and features of RNAi therapeutics

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The Science of RNA interference (RNAi)

This slide deck provides an overview of the science of RNA interference (RNAi), including mechanism of action and delivery platforms.

Click below to learn about how different siRNA delivery platforms work.

Publication Date

Dec 2, 2020

Journal

Nucleic Acids Res.

Authors

Brown CR, Gupta S, Qin J et al. 

Click here to learn more about how Alnylam is optimizing RNAi delivery.