Transthyretin (ATTR) amyloidosis

Explore our collection of clinical education resources to understand more about the diagnosis, epidemiology, disease burden, and management of transthyretin (ATTR) amyloidosis. 

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ATTRv Amyloidosis Hub

This Resource Center, provided by PRIME Education and supported by Alnylam Pharmaceuticals, contains downloadable resources and practical tools to support coordinated, multidisciplinary care and facilitate timely, comprehensive diagnostic evaluations for patients with ATTRv (also known as hATTR) amyloidosis.

Posted: August 05, 2024

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Hereditary ATTR Amyloidosis: A Closer Look at the V122I Variant

V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.

 

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Symptoms and Disease Burden of ATTR

This slide deck provides an overview of the symptoms and disease burden of ATTR.

 

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Screening, Recognition, and Barriers to Diagnosis of ATTR

This deck highlights the screening, recognition, and barriers of diagnosis in ATTR.

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Hereditary ATTR Amyloidosis: A Closer Look at the V122I Variant

V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.

 

Therapeutic Area Congress Resources

 

 

Publications

Publication Date

May 2020

Journal

Amyloid

Authors

Ola Akinboboye, Keyur Shah, Alberta L. Warner, et al.

Publication Date

August 2021

Journal

Circulation: Genomic and Precision Medicine

Authors

Barry Trachtenberg, Sachin Shah, Robert Nussbaum et al 

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ATTR Diagnostic and Staging Tools

This deck highlights diagnostic and staging tools for assessing patients with ATTR.

 

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Hereditary ATTR Amyloidosis: A Closer Look at the V122I Variant

V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.

 

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ATTR Screening and Carrier Management

This deck highlights tools for ATTR screening and recommendations for the management of hATTR carriers.

 

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Diagnosis of ATTR

This deck highlights the red flag symptoms of ATTR and the tools to help achieve an accurate diagnosis.

 

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ATTR Amyloidosis Disease State Handout

This handout provides an overview of ATTR amyloidosis manifestations and the diagnostic tools that can be used to assess their presentation.
 

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Carpal Tunnel Release Surgery Handout

This handout provides an overview of two diagnostic algorithms for ATTR amyloidosis in patients with carpal tunnel syndrome.

 

Therapeutic Area Congress Resources

 

 

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Musculoskeletal Manifestations Associated with ATTR Amyloidosis

This slide deck provides disease education on ATTR amyloidosis, focusing on the musculoskeletal manifestations associated with the disease and their importance for early diagnosis and patient care.

 

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Hereditary ATTR Amyloidosis: A Closer Look at the V122I Variant

V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.

 

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Symptoms and Disease Burden of ATTR

This slide deck provides an overview of the symptoms and disease burden of ATTR.

 

Therapeutic Area Congress Resources

 

 

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Hereditary ATTR Amyloidosis: A Closer Look at the V122I Variant

V122I is the most common variant of hATTR amyloidosis in the United States and is most prevalent in patients of African American descent. Compared to other variants, patients with the V122I variant experience significant disease burden and poorer outcomes.

 

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ATTR Disease Management

This deck highlights management and monitoring of patients with ATTR.

 

 

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ATTR Management Guidelines

This deck highlights published guidelines on diagnosis, treatment and disease management of ATTR.

 

 

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ATTR Screening and Carrier Management

This deck highlights tools for ATTR screening and recommendations for the management of hATTR carriers.

 

 

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ATTRv-PN Expert Opinion Slide Deck

Recommendations from a panel of experts for the diagnosis and treatment of hereditary transthyretin amyloidosis with polyneuropathy in the United States.